Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol HOOK3
Synonyms HK3
Gene Description HOOK3, hook microtubule-tethering protein 3, is a component of the FHF complex that regulates vesicle trafficking (PMID: 18799622, PMID: 31217419). Overexpression of Hook3 has been associated with advanced stage prostate cancer (PMID: 26230842) and HOOK3-RET fusions have been identified in papillary thyroid carcinoma (PMID: 17639057).


Additional content available in CKB BOOST