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Gene Symbol RAD54L
Synonyms hHR54 | HR54 | hRAD54 | RAD54A
Gene Description RAD54L, RAD54-like, is a member of the SWI2/SNF2 family of dsDNA-dependent ATPases, which functions in homologous recombination in DNA repair (PMID: 20089461, PMID: 21704205). Overexpression of Rad54l has been demonstrated in non-small cell lung cancer (PMID: 21412013).
NCBI Gene ID Chromosome Map Location Canonical Transcript Gene Role
8438 1 1p34.1 NM_001142548 Unknown

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Variant Impact Protein Effect Variant Description Associated with drug Resistance
inact mut unknown loss of function RAD54L inact mut indicates that this variant results in a loss of function of the Rad54l protein. However, the specific amino acid change has not been identified.
mutant unknown unknown RAD54L mutant indicates an unspecified mutation in the RAD54L gene.