Gene Detail

Gene Symbol RSPO3
Synonyms CRISTIN1 | PWTSR | THSD2
Gene Description RSPO3, R-spondin 3, encodes for one of the secreted proteins in the TSR1-containing protein family, which plays a role in canonical Wnt signaling due to its furin repeat domains (PMID: 24980904). RSPO3 fusions with PTPRK have been frequently identified in colorectal cancer (PMID: 26924569).
Entrez Id 84870
Chromosome 6
Map Location 6q22.33
Canonical Transcript NM_032784


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