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Gene Symbol CDK10
Gene Description CDK10, cyclin-dependent kinase 10, binds Cyclin M (encoded by FAM58A) to regulate the transcription factor, ETS2 (PMID: 24218572), and functions in organization of the actin cytoskeleton and ciliogenesis (PMID: 27104747, PMID: 28178678). Decreased expression of Ckd10 has been observed and gastric cancer (PMID: 29512714, PMID: 28928881) and reported in endocrine therapy resistant breast cancer (PMID: 18242510).
Additional content available in CKB BOOST