Gene Detail

Gene Symbol CDK10
Synonyms ALSAS | PISSLRE
Gene Description CDK10, cyclin-dependent kinase 10, binds Cyclin M (encoded by FAM58A) to regulate the transcription factor, ETS2 (PMID: 24218572), and functions in organization of the actin cytoskeleton and ciliogenesis (PMID: 27104747, PMID: 28178678). Decreased expression of Ckd10 has been observed and gastric cancer (PMID: 29512714, PMID: 28928881) and reported in endocrine therapy resistant breast cancer (PMID: 18242510).
Entrez Id 8558
Chromosome 16
Map Location 16q24.3
Canonical Transcript NM_052988


Additional content available in CKB BOOST