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Gene Symbol CBFA2T3
Synonyms ETO2 | MTG16 | MTGR2 | RUNX1T3 | ZMYND4
Gene Description CBFA2T3, CBFA2/RUNX1 partner transcriptional co-repressor 3, is a member of the ETO family of proteins and a transcriptional repressor that mediates interaction with other corepressors, transcription factors and chromatin-modifying enzymes, and plays a role in cellular proliferation and differentiation (PMID: 15203199, PMID: 16407974). Fusions with CBFA2T3 have been identified in acute erythroid leukemia (PMID: 23032695), and acute myeloid leukemia (PMID: 30592296).


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