Gene Detail

Gene Symbol CBFB
Synonyms PEBP2B
Gene Description CBFB, core-binding factor, beta subunit, is the non DNA-binding regulatory subunit that complexes with Runx1, Runx2, or Runx3 proteins to make up the core-binding factors that are involved in regulating hematopoiesis (PMID: 15156179). CBFB is frequently involved in chromosomal translocations in leukemia (PMID: 8351518).
Entrez Id 865
Chromosome 16
Map Location 16q22.1
Canonical Transcript NM_001755

Additional content available in CKB BOOST