Gene Detail


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Gene Symbol CCN6
Synonyms LIBC | PPAC | PPD | PPRD | WISP-3 | WISP3
Gene Description CCN6, cellular communication network factor 6, encodes a secreted matrix-associated protein that binds to multiple receptors and regulates signaling pathways governing development and epithelial-mesenchymal transition (PMID: 29357008). CCN6 mutations and decreased Ccn6 expression has been identified in hepatocellular carcinoma (PMID: 30793395), gastric (PMID: 26997449), colon (PMID: 9843955), and breast cancer (PMID: 10499627).
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