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Gene Symbol WASF1
Synonyms NEDALVS | SCAR1 | WAVE | WAVE1
Gene Description WASF1, WASP family member 1, is part of the WAVE complex that regulates actin dynamic and membrane protrusion, thus contributing to cell migration (PMID: 25145849). Loss of WASF1 has been identified in prostate cancer (PMID: 25906751), overexpression of Wasf1 was observed in acute myeloblastic leukemia (PMID: 21281239), and a WASF1-BRAF fusion has been identified in advanced solid tumors (PMID: 29320312).


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