Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : email@example.com
|Synonyms||EST182763 | MRP7 | SIMRP7|
|Gene Description||ABCC10, ATP binding cassette subfamily C member 10, is a member of the multidrug resistance protein family that encodes a lipophilic anion efflux transporter and plays a role in mediating drug resistance (PMID: 14576857, PMID: 16868766, PMID: 24103790). Expression of ABCC10 has been identified in breast cancer with increased expression observed in ERBB2 (HER2)-positive and ESR1 (ER)-positive breast cancers (PMID: 24937672), and decreased ABCC10 expression has been associated with aggressive colorectal cancer (PMID: 22294766).|