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|Synonyms||WARTS | wts|
|Gene Description||LATS1, large tumor suppressor kinase 1, is a serine/threonine-protein kinase that negatively regulates YAP1 in the Hippo signaling pathway, which plays a role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (PMID: 24026096). LATS1 may play a role as a tumor suppressor in human cancer (PMID: 24026096, PMID: 28644436).|