Gene Detail

Gene Symbol LATS1
Synonyms WARTS | wts
Gene Description LATS1, serine/threonine-protein kinase LATS1, is a negative regulator of YAP1 in the Hippo signaling pathway, which plays a role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. LATS1 plays a role as a tumor suppressor in human cancer (PMID: 24026096).
Entrez Id 9113
Chromosome 6
Map Location 6q25.1
Canonical Transcript NM_004690

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