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Gene Symbol INA
Synonyms NEF5 | NF-66 | TXBP-1
Gene Description INA, internexin neuronal intermediate filament protein alpha, also known as alpha-internexin is a type IV intermediate filament protein of the cytoskeleton that may play a role in cell differentiation (PMID: 29940892). Altered expression of Ina has been reported in medulloblastomas, neuroblastomas, while loss of expression has been observed in gastroenteropancreatic neuroendocrine neoplasms (PMID: 29940892), and an FGFR2-INA fusion has been reported in low-grade mixed neuronal-glial tumors (PMID: 29767381) and intrahepatic cholangiocarcinoma (PMID: 31109923).


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