Gene Detail

Gene Symbol DYRK1B
Synonyms AOMS3 | MIRK
Gene Description DYRK1B, dual specificity tyrosine phosphorylation regulated kinase 1B, encodes for a serine/threonine kinase, which plays a role in the differentiation of muscle cells via regulation of the cell cycle, survival, and transcription (PMID: 24955215, PMID: 29193696). DYRK1B amplification and overexpression have been observed in a number of cancers including ovarian, pancreatic (PMID: 17583556), and breast cancer (PMID: 28554575).
Entrez Id 9149
Chromosome 19
Map Location 19q13.2
Canonical Transcript NM_004714


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