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Gene Symbol EXO1
Synonyms HEX1 | hExoI
Gene Description EXO1, exonuclease 1, is a member of the Rad2/XPG nuclease family that plays a role in DNA replication, checkpoint progression, and DNA repair (PMID: 27098756, PMID: 30585186, PMID: 25956862). EXO1 overexpression has been observed in hepatocellular carcinoma (PMID: 30328366) and EXO1 mutations have been identified in breast cancer (PMID: 30947698) and pancreatic cancer (PMID: 29940740).


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