Gene Detail

Gene Symbol MAP3K13
Synonyms LZK | MEKK13 | MLK
Gene Description MAP3K13, mitogen-activated protein kinase kinase kinase 13, is a member of the mixed lineage kinase (MLK) protein family that is involved in JNK pathway signaling (PMID: 11726277). MAP3K13 mutations have been identified in breast cancer (PMID: 22722201) and amplification has been observed in head and neck squamous cell carcinoma (PMID: 28760853).
Entrez Id 9175
Chromosome 3
Map Location 3q27.2
Canonical Transcript

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