Gene Detail
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| Gene Symbol | MAP3K13 | ||||||||||
| Synonyms | LZK | MEKK13 | MLK | ||||||||||
| Gene Description | MAP3K13, mitogen-activated protein kinase kinase kinase 13, is a member of the mixed lineage kinase (MLK) protein family that is involved in JNK pathway signaling (PMID: 11726277). MAP3K13 mutations have been identified in breast cancer (PMID: 22722201) and amplification has been observed in head and neck squamous cell carcinoma (PMID: 28760853). | ||||||||||
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