Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol NAPRT
Synonyms NAPRT1 | PP3856
Gene Description NAPRT, nicotinate phosphoribosyltransferase 1, is an enzyme catalyzing NAD synthesis from nicotinic acid, therefore regulating cellular oxidative stress (PMID: 17604275), and extracellular NAPRT1 may play a role in inflammation (PMID: 32266141). NAPRT1 is expressed in a wide variety of tumor cell lines (PMID: 26675378) and amplification and/or overexpression of NAPRT has been observed in prostate, ovarian, and pancreatic cancers (PMID: 32266141).


Additional content available in CKB BOOST