Gene Detail


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Gene Symbol ACVRL1
Synonyms ACVRLK1 | ALK-1 | ALK1 | HHT | HHT2 | ORW2 | SKR3 | TSR-I
Gene Description ACVRL1, activin A receptor like type 1, encodes a transmembrane type I receptor of the TGF-beta superfamily of ligands and plays a role in angiogenesis, vascular remodeling, and the regulation of endothelial cells (PMID: 20587022, PMID: 28927913). ACVRL1 overexpression has been identified in colorectal cancer (PMID: 29636300) and breast cancer (PMID: 27742676).
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