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Gene Symbol CD86
Synonyms B7-2 | B7.2 | B70 | CD28LG2 | LAB72
Gene Description CD86, CD86 molecule, is a costimulatory receptor that interacts with CD28 and cytotoxic T-lymphocyte associated antigen 4 (CTLA4), and plays an important role in homeostasis of regulatory T cells, and regulates self-tolerance and activation of T cells (PMID: 15771580, PMID: 9492990). Expression of CD86 has been identified in nasopharyngeal carcinoma (PMID: 17524139).
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