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Gene Symbol TMEM59
Synonyms C1orf8 | DCF1 | HSPC001 | PRO195 | UNQ169
Gene Description TMEM59, transmembrane protein 59, regulates glycosylation and secretion of the amyloid precursor protein (PMID: 20427278), promotes autophagy in response to bacteria infection (PMID: 23376921), and facilitates Wnt signaling through signalosome formation (PMID: 29632210). Loss of TMEM59 regulation has been associated with gastric cancer progression (PMID: 30778372).
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