Gene Detail


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Gene Symbol CD44
Synonyms CDW44 | CSPG8 | ECM-III | ECMR-III | H-CAM | HCELL | Hermes-1 | HUTCH-1 | HUTCH-I | IN | LHR | MC56 | MDU2 | MDU3 | MIC4 | Pgp1
Gene Description CD44, CD44 molecule (Indian blood group), is non-kinase transmembrane glycoprotein that binds the ligand, hyaluronan, and plays a role in cell proliferation and cell motility (PMID: 28326306, PMID: 29747682). Overexpression of CD44 has been observed in gastric cancer (PMID: 32219571), is commonly found in epithelial originated tumors (PMID: 27200096), and has been associated with poor prognosis in glioma (PMID: 32232385) and glioblastoma (PMID: 32099472).
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