Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
| Gene Symbol | CD44 | ||||||||||
| Synonyms | CDW44 | CSPG8 | ECM-III | ECMR-III | H-CAM | HCELL | Hermes-1 | HUTCH-1 | HUTCH-I | IN | LHR | MC56 | MDU2 | MDU3 | MIC4 | Pgp1 | ||||||||||
| Gene Description | CD44, CD44 molecule (Indian blood group), is non-kinase transmembrane glycoprotein that binds the ligand, hyaluronan, and plays a role in cell proliferation and cell motility (PMID: 28326306, PMID: 29747682). Overexpression of CD44 has been observed in gastric cancer (PMID: 32219571), is commonly found in epithelial originated tumors (PMID: 27200096), and has been associated with poor prognosis in glioma (PMID: 32232385) and glioblastoma (PMID: 32099472). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
