Gene Detail

Gene Symbol MDC1
Synonyms NFBD1
Gene Description MDC1, mediator of DNA damage checkpoint 1, is an adaptor protein that regulates the assembly of DNA damage foci in response to DNA damage (PMID: 21326949). Mutations of MDC1 have been associated with poor prognosis in breast cancer patients (PMID: 28513990).
Entrez Id 9656
Chromosome 6
Map Location 6p21.33
Canonical Transcript NM_014641


Additional content available in CKB BOOST