Gene Detail

Gene Symbol CD74
Synonyms DHLAG | HLADG | Ia-GAMMA | II | p33
Gene Description CD74, CD74 molecule, encodes for an integral membrane protein that acts as an MHC class II chaperone and plays a role in the signal transduction of pathways related to cell survival and proliferation (PMID: 16484589). CD74 overexpression as well as fusions with ROS1 and NRG1 have been linked to several tumor types including lung (PMID: 21228923, PMID: 23877438).
Entrez Id 972
Chromosome 5
Map Location 5q33.1
Canonical Transcript NM_001025159


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