Gene Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at :

Gene Symbol KMT2B
Synonyms CXXC10 | DYT28 | HRX2 | MLL1B | MLL2 | MLL4 | MRD68 | TRX2 | WBP-7 | WBP7
Gene Description KMT2B, lysine methyltransferase 2B, is responsible for the methylation of H3K4, a post-translational modification that leads to the regulation of gene expression, the cell cycle, and embryonic development (PMID: 27839873, PMID: 25998713). KMT2B mutations have been identified in a variety of tumor types including endometrial cancer, lung cancer, and hepatic cancer (PMID: 25998713).
Additional content available in CKB BOOST