Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Synonyms||CDC2L1 | CDK11 | CDK11-p110 | CDK11-p46 | CDK11-p58 | CLK-1 | p58 | p58CDC2L1 | p58CLK-1 | PITSLREA | PK58|
|Gene Description||CDK11B, cyclin-dependent kinase 11B, is also known as CDC2L1 and is one of eleven isoforms encoding CDK11, which is also encoded by CDK11A and it is not clear which CDK11 isoforms (p46, p58, and p110) correspond to CDK11 A or B (PMID: 27049727). CDK11 plays a role in the regulation of cell growth, proliferation, and apoptosis (PMID: 24007862) and aberrant expression of Cdk11 has a role in tumor progression in multiple tumor types (PMID: 27049727, PMID: 28262798, PMID: 27207777, PMID: 26470709).|