Gene Detail
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| Gene Symbol | PJA2 | ||||||||||
| Synonyms | Neurodap1 | RNF131 | ||||||||||
| Gene Description | PJA2, praja ring finger ubiquitin ligase 2, is an E3 ubiquitin ligase that plays a role in regulation of PKA signaling and gene expression (PMID: 30021253, PMID: 24083380). Overexpression of Pja2 has been observed in papillary thyroid cancer (PMID: 22948757) and a PJA2-BRAF fusion has been identified in lung cancer (PMID: 30831205). | ||||||||||
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