Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol MED12
Synonyms ARC240 | CAGH45 | FGS1 | HOPA | Kto | MED12S | OHDOX | OKS | OPA1 | TNRC11 | TRAP230
Gene Description MED12, mediator complex subunit 12, is a subunit of Mediator, a complex involved in regulating expression of most RNA polymerase II transcripts (PMID: 24123922). MED12 acts in Gli3-dependent Sonic hedgehog signaling and epigenetic silencing of genes, and is mutated in several cancers (PMID: 24123922).


Additional content available in CKB BOOST