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Gene | BTK |
Variant | A582T |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | BTK A582T lies within the protein kinase domain of the Btk protein (UniProt.org). A582T has not been characterized in the scientific literature and therefore, its effect on Btk protein function is unknown (PubMed, Apr 2024). |
Associated Drug Resistance | |
Category Variants Paths |
BTK mutant BTK A582T |
Transcript | NM_000061.3 |
gDNA | chrX:g.101353876C>T |
cDNA | c.1744G>A |
Protein | p.A582T |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_000061.2 | chrX:g.101353876C>T | c.1744G>A | p.A582T | RefSeq | GRCh38/hg38 |
NM_000061.3 | chrX:g.101353876C>T | c.1744G>A | p.A582T | RefSeq | GRCh38/hg38 |
NM_000061 | chrX:g.101353876C>T | c.1744G>A | p.A582T | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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