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|Variant||ETV6 - PDGFRB|
|Protein Effect||gain of function|
|Gene Variant Descriptions||ETV6-PDGFRB results from the fusion of ETV6 and PDGFRB, demonstrating the ability to stimulate proliferation and differentiation of progenitor cells and activation of transcription factors (PMID: 22271894).|
|Associated Drug Resistance|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Molecular Profile||Protein Effect||Treatment Approaches|
|ETV6 - PDGFRB||gain of function|