Gene Variant Detail

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Gene ASXL1
Variant K163T
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ASXL1 K163T lies within the nuclear localization signal motif 1 of the Asxl1 protein (UniProt.org). K163T has not been characterized in the scientific literature and therefore, its effect on Asxl1 protein function is unknown (PubMed, Mar 2020).
Associated Drug Resistance

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Transcript NM_015338
gDNA chr20:g.32429354A>C
cDNA c.488A>C
Protein p.K163T
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_015338 chr20:g.32429354A>C c.488A>C p.K163T RefSeq GRCh38/hg38
XM_017027706 chr20:g.32429354A>C c.488A>C p.K163T RefSeq GRCh38/hg38
XM_006723727 chr20:g.32429357A>C c.488A>C p.K163T RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Molecular Profile Protein Effect Treatment Approaches
ASXL1 K163T unknown
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References