Gene Variant Detail

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Gene BCORL1
Variant A157T
Impact List missense
Protein Effect unknown
Gene Variant Descriptions BCORL1 A157T does not lie within any known functional domains of the Bcorl1 protein (UniProt.org). A157T has been identified in sequencing studies (PMID: 25186949), but has not been biochemically characterized and therefore, its effect on Bcorl1 protein function is unknown (PubMed, Apr 2020).
Associated Drug Resistance

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Transcript NM_021946
gDNA chrX:g.130013241G>A
cDNA c.469G>A
Protein p.A157T
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_017029722 chrX:g.130013241G>A c.469G>A p.A157T RefSeq GRCh38/hg38
XM_006724776 chrX:g.130013241G>A c.469G>A p.A157T RefSeq GRCh38/hg38
XM_006724777 chrX:g.130013241G>A c.469G>A p.A157T RefSeq GRCh38/hg38
XM_005262456 chrX:g.130013241G>A c.469G>A p.A157T RefSeq GRCh38/hg38
XM_005262455 chrX:g.130013241G>A c.469G>A p.A157T RefSeq GRCh38/hg38
NM_001184772 chrX:g.130013241G>A c.469G>A p.A157T RefSeq GRCh38/hg38
XM_017029721 chrX:g.130013241G>A c.469G>A p.A157T RefSeq GRCh38/hg38
XM_005262454 chrX:g.130013241G>A c.469G>A p.A157T RefSeq GRCh38/hg38
XM_005262452 chrX:g.130013241G>A c.469G>A p.A157T RefSeq GRCh38/hg38
NM_021946 chrX:g.130013241G>A c.469G>A p.A157T RefSeq GRCh38/hg38
XM_005262453 chrX:g.130013241G>A c.469G>A p.A157T RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Molecular Profile Protein Effect Treatment Approaches
BCORL1 A157T unknown