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Gene | KMT2A |
Variant | P3407L |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | KMT2A P3407L does not lie within any known functional domains of the Kmt2a protein (UniProt.org). P3407L has not been characterized in the scientific literature and therefore, its effect on Kmt2a protein function is unknown (PubMed, Jan 2022). |
Associated Drug Resistance |
Transcript | NM_005933.3 |
gDNA | chr11:g.118506121C>T |
cDNA | c.10220C>T |
Protein | p.P3407L |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_005933.3 | chr11:g.118506121C>T | c.10220C>T | p.P3407L | RefSeq | GRCh38/hg38 |
NM_005933 | chr11:g.118506121C>T | c.10220C>T | p.P3407L | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
KMT2A P3407L | unknown |