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Gene | SF3B1 |
Variant | K121M |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | SF3B1 K121M does not lie within any known functional domains of the Sf3b1 protein (UniProt.org). K121M has not been characterized in the scientific literature and therefore, its effect on Sf3b1 protein function is unknown (PubMed, Feb 2021). |
Associated Drug Resistance |
Transcript | NM_012433.3 |
gDNA | chr2:g.197420481T>A |
cDNA | c.362A>T |
Protein | p.K121M |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_001005526 | chr2:g.197420481T>A | c.362A>T | p.K121M | RefSeq | GRCh38/hg38 |
NM_001308824.1 | chr2:g.197420481T>A | c.362A>T | p.K121M | RefSeq | GRCh38/hg38 |
NM_001308824 | chr2:g.197420481T>A | c.362A>T | p.K121M | RefSeq | GRCh38/hg38 |
NM_012433 | chr2:g.197420481T>A | c.362A>T | p.K121M | RefSeq | GRCh38/hg38 |
NM_012433.3 | chr2:g.197420481T>A | c.362A>T | p.K121M | RefSeq | GRCh38/hg38 |
NM_001005526.2 | chr2:g.197420481T>A | c.362A>T | p.K121M | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
SF3B1 K121M | unknown |