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Gene | FGFR1 |
Variant | T658P |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | FGFR1 T658P lies within the protein kinase domain of the Fgfr1 protein (UniProt.org). T658P has been identified in the scientific literature (PMID: 27608415, PMID: 23817572), but has not been biochemically characterized and therefore, its effect on Fgfr1 protein function is unknown (PubMed, Mar 2024). |
Associated Drug Resistance | |
Category Variants Paths |
FGFR1 mutant FGFR1 T658P |
Transcript | NM_023110.3 |
gDNA | chr8:g.38414784T>G |
cDNA | c.1972A>C |
Protein | p.T658P |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
XM_006716304.2 | chr8:g.38414784T>G | c.1972A>C | p.T658P | RefSeq | GRCh38/hg38 |
XM_017013221.1 | chr8:g.38414784T>G | c.1972A>C | p.T658P | RefSeq | GRCh38/hg38 |
NM_023110.3 | chr8:g.38414784T>G | c.1972A>C | p.T658P | RefSeq | GRCh38/hg38 |
XM_006716303.4 | chr8:g.38414784T>G | c.1972A>C | p.T658P | RefSeq | GRCh38/hg38 |
XM_006716303 | chr8:g.38414784T>G | c.1972A>C | p.T658P | RefSeq | GRCh38/hg38 |
XM_006716304.1 | chr8:g.38414784T>G | c.1972A>C | p.T658P | RefSeq | GRCh38/hg38 |
XM_017013221.2 | chr8:g.38414784T>G | c.1972A>C | p.T658P | RefSeq | GRCh38/hg38 |
XM_017013221 | chr8:g.38414784T>G | c.1972A>C | p.T658P | RefSeq | GRCh38/hg38 |
NM_023110 | chr8:g.38414784T>G | c.1972A>C | p.T658P | RefSeq | GRCh38/hg38 |
XM_006716303.3 | chr8:g.38414784T>G | c.1972A>C | p.T658P | RefSeq | GRCh38/hg38 |
XM_006716304 | chr8:g.38414784T>G | c.1972A>C | p.T658P | RefSeq | GRCh38/hg38 |
NM_023110.2 | chr8:g.38414784T>G | c.1972A>C | p.T658P | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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