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|Variant||FGFR2 - OGA|
|Gene Variant Descriptions||FGFR2-OGA results from the fusion of FGFR2 and OGA (PMID: 24550739). FGFR2-OGA has been identified in intrahepatic cholangiocarcinoma and is associated with increased Fgfr2 expression and phosphorylation of Frs2 and Erk in patient tissue (PMID: 24550739), but has not been fully biochemically characterized and therefore, the effect on protein function is unknown (PubMed, May 2020).|
|Associated Drug Resistance|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Molecular Profile||Protein Effect||Treatment Approaches|
|FGFR2 - OGA||unknown|