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Gene ERBB4
Variant R525S
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ERBB4 R525S lies within the extracellular domain of the Erbb4 protein (UniProt.org). R525S has been identified in sequencing studies (PMID: 26960398), but has not been biochemically characterized and therefore, its effect on Erbb4 protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

ERBB4 mutant ERBB4 R525S

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Transcript NM_005235.3
gDNA chr2:g.211679101G>T
cDNA c.1573C>A
Protein p.R525S
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_005246376.3 chr2:g.211679101G>T c.1573C>A p.R525S RefSeq GRCh38/hg38
NM_001042599.1 chr2:g.211679101G>T c.1573C>A p.R525S RefSeq GRCh38/hg38
NM_001042599.1 chr2:g.211679101G>T c.1573C>A p.R525S RefSeq GRCh38/hg38
NM_001042599 chr2:g.211679101G>T c.1573C>A p.R525S RefSeq GRCh38/hg38
XM_006712364.4 chr2:g.211679101G>T c.1573C>A p.R525S RefSeq GRCh38/hg38
XM_005246377 chr2:g.211679101G>T c.1573C>A p.R525S RefSeq GRCh38/hg38
XM_005246377.4 chr2:g.211679101G>T c.1573C>A p.R525S RefSeq GRCh38/hg38
XM_005246376 chr2:g.211679101G>T c.1573C>A p.R525S RefSeq GRCh38/hg38
XM_006712364 chr2:g.211679101G>T c.1573C>A p.R525S RefSeq GRCh38/hg38
NM_005235.3 chr2:g.211679101G>T c.1573C>A p.R525S RefSeq GRCh38/hg38
XM_005246377.3 chr2:g.211679101G>T c.1573C>A p.R525S RefSeq GRCh38/hg38
NM_005235 chr2:g.211679101G>T c.1573C>A p.R525S RefSeq GRCh38/hg38
NM_005235.2 chr2:g.211679101G>T c.1573C>A p.R525S RefSeq GRCh38/hg38
XM_006712364.3 chr2:g.211679101G>T c.1573C>A p.R525S RefSeq GRCh38/hg38
XM_005246376.4 chr2:g.211679101G>T c.1573C>A p.R525S RefSeq GRCh38/hg38

Filtering

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References