Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
Gene | RET |
Variant | R1013del |
Impact List | deletion |
Protein Effect | unknown |
Gene Variant Descriptions | RET R1013del results in the deletion of an amino acid in the protein kinase domain of the Ret protein at amino acid 1013 (UniProt.org). R1013del has not been characterized in the scientific literature and therefore, its effect on Ret protein function is unknown (PubMed, Aug 2024). |
Associated Drug Resistance | |
Category Variants Paths |
RET mutant RET R1013del |
Transcript | NM_020975.6 |
gDNA | chr10:g.43124980_43124982delAGA |
cDNA | c.3037_3039delAGA |
Protein | p.R1013delR |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_020630.5 | chr10:g.43124980_43124982delAGA | c.3037_3039delAGA | p.R1013delR | RefSeq | GRCh38/hg38 |
NM_001406761.1 | chr10:g.43126701_43126703delTGG | c.3037_3039delTGG | p.W1013delW | RefSeq | GRCh38/hg38 |
NM_020975 | chr10:g.43124980_43124982delAGA | c.3037_3039delAGA | p.R1013delR | RefSeq | GRCh38/hg38 |
NM_020630 | chr10:g.43124980_43124982delAGA | c.3037_3039delAGA | p.R1013delR | RefSeq | GRCh38/hg38 |
NM_001406760.1 | chr10:g.43124980_43124982delAGA | c.3037_3039delAGA | p.R1013delR | RefSeq | GRCh38/hg38 |
NM_001406766.1 | chr10:g.43128249_43128251delATG | c.3037_3039delATG | p.M1013delM | RefSeq | GRCh38/hg38 |
NM_020630.7 | chr10:g.43124980_43124982delAGA | c.3037_3039delAGA | p.R1013delR | RefSeq | GRCh38/hg38 |
NM_001406759.1 | chr10:g.43124980_43124982delAGA | c.3037_3039delAGA | p.R1013delR | RefSeq | GRCh38/hg38 |
NM_001406767.1 | chr10:g.43128249_43128251delATG | c.3037_3039delATG | p.M1013delM | RefSeq | GRCh38/hg38 |
NM_020975.6 | chr10:g.43124980_43124982delAGA | c.3037_3039delAGA | p.R1013delR | RefSeq | GRCh38/hg38 |
NM_001406765.1 | chr10:g.43126707_43126709delGAA | c.3037_3039delGAA | p.E1013delE | RefSeq | GRCh38/hg38 |
NM_001406762.1 | chr10:g.43126701_43126703delTGG | c.3037_3039delTGG | p.W1013delW | RefSeq | GRCh38/hg38 |
NM_001406763.1 | chr10:g.43126707_43126709delGAA | c.3037_3039delGAA | p.E1013delE | RefSeq | GRCh38/hg38 |
NM_001406764.1 | chr10:g.43126701_43126703delTGG | c.3037_3039delTGG | p.W1013delW | RefSeq | GRCh38/hg38 |
NM_001406744.1 | chr10:g.43124980_43124982delAGA | c.3037_3039delAGA | p.R1013delR | RefSeq | GRCh38/hg38 |
NM_001406743.1 | chr10:g.43124980_43124982delAGA | c.3037_3039delAGA | p.R1013delR | RefSeq | GRCh38/hg38 |
NM_020975.5 | chr10:g.43124980_43124982delAGA | c.3037_3039delAGA | p.R1013delR | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|