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Gene FGFR1
Variant W666R
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR1 W666R lies within the protein kinase domain of the Fgfr1 protein (UniProt.org). W666R has not been characterized and therefore, its effect on Fgfr1 protein function is unknown (PubMed, Aug 2023).
Associated Drug Resistance
Category Variants Paths

FGFR1 mutant FGFR1 W666R

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Transcript NM_023110.3
gDNA chr8:g.38414611A>T
cDNA c.1996T>A
Protein p.W666R
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_023110 chr8:g.38414611A>T c.1996T>A p.W666R RefSeq GRCh38/hg38
XM_006716303 chr8:g.38414611A>T c.1996T>A p.W666R RefSeq GRCh38/hg38
NM_023110.2 chr8:g.38414611A>T c.1996T>A p.W666R RefSeq GRCh38/hg38
XM_017013221.1 chr8:g.38414611A>T c.1996T>A p.W666R RefSeq GRCh38/hg38
XM_006716304.1 chr8:g.38414611A>T c.1996T>A p.W666R RefSeq GRCh38/hg38
XM_017013221.2 chr8:g.38414611A>T c.1996T>A p.W666R RefSeq GRCh38/hg38
XM_017013221 chr8:g.38414611A>T c.1996T>A p.W666R RefSeq GRCh38/hg38
NM_023110.3 chr8:g.38414611A>T c.1996T>A p.W666R RefSeq GRCh38/hg38
XM_006716303.3 chr8:g.38414611A>T c.1996T>A p.W666R RefSeq GRCh38/hg38
XM_006716304.2 chr8:g.38414611A>T c.1996T>A p.W666R RefSeq GRCh38/hg38
XM_006716304 chr8:g.38414611A>T c.1996T>A p.W666R RefSeq GRCh38/hg38
XM_006716303.4 chr8:g.38414611A>T c.1996T>A p.W666R RefSeq GRCh38/hg38

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References