Gene Variant Detail

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Gene FGFR1
Variant L573M
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR1 L573M lies within the protein kinase domain of the Fgfr1 protein (UniProt.org). L573M has not been characterized in the scientific literature and therefore, its effect on Fgfr1 protein function is unknown (PubMed, Dec 2023).
Associated Drug Resistance
Category Variants Paths

FGFR1 mutant FGFR1 L573M

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Transcript NM_023110.3
gDNA chr8:g.38416007G>T
cDNA c.1717C>A
Protein p.L573M
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_006716311.1 chr8:g.38414623G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
XM_024447097.1 chr8:g.38415983G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
XM_006716303.4 chr8:g.38416007G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
NM_023110 chr8:g.38416007G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
XM_006716309 chr8:g.38415983G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
XM_024447097.1 chr8:g.38415983G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
XM_006716310.3 chr8:g.38414623G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
XM_006716304.1 chr8:g.38416007G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
XM_006716310 chr8:g.38414623G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
XM_006716310.4 chr8:g.38414623G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
XM_017013221 chr8:g.38416007G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
XM_006716304 chr8:g.38416007G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
XM_006716312.2 chr8:g.38414623G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
NM_001174066.2 chr8:g.38414623G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
XM_006716303 chr8:g.38416007G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
XM_006716304.2 chr8:g.38416007G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
NM_001174066 chr8:g.38414623G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
XM_006716303.3 chr8:g.38416007G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
XM_017013221.2 chr8:g.38416007G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
XM_017013221.1 chr8:g.38416007G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
NM_001174066.1 chr8:g.38414623G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
NM_023110.2 chr8:g.38416007G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
XM_006716311.1 chr8:g.38414623G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
XM_006716312 chr8:g.38414623G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
NM_023105.2 chr8:g.38414623G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
NM_023105 chr8:g.38414623G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
XM_006716311 chr8:g.38414623G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
NM_023110.3 chr8:g.38416007G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
NM_023105.3 chr8:g.38414623G>T c.1717C>A p.L573M RefSeq GRCh38/hg38
XM_006716312.2 chr8:g.38414623G>T c.1717C>A p.L573M RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References