Gene Variant Detail

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Gene FGFR1
Variant D652G
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR1 D652G lies within the protein kinase domain of the Fgfr1 protein (UniProt.org). D652G has been identified in sequencing studies (PMID: 26920151, PMID: 32059187, PMID: 35836307), but has not been biochemically characterized and therefore, its effect on Fgfr1 protein function is unknown (PubMed, Aug 2023).
Associated Drug Resistance
Category Variants Paths

FGFR1 mutant FGFR1 D652G

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Transcript NM_023110.3
gDNA chr8:g.38414801T>C
cDNA c.1955A>G
Protein p.D652G
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_023110.3 chr8:g.38414801T>C c.1955A>G p.D652G RefSeq GRCh38/hg38
XM_006716303 chr8:g.38414801T>C c.1955A>G p.D652G RefSeq GRCh38/hg38
XM_017013219.2 chr8:g.38414888T>C c.1955A>G p.D652G RefSeq GRCh38/hg38
XM_017013221.2 chr8:g.38414801T>C c.1955A>G p.D652G RefSeq GRCh38/hg38
XM_017013220.2 chr8:g.38414888T>C c.1955A>G p.D652G RefSeq GRCh38/hg38
XM_017013219 chr8:g.38414888T>C c.1955A>G p.D652G RefSeq GRCh38/hg38
XM_017013221.1 chr8:g.38414801T>C c.1955A>G p.D652G RefSeq GRCh38/hg38
XM_006716303.3 chr8:g.38414801T>C c.1955A>G p.D652G RefSeq GRCh38/hg38
NM_023110.2 chr8:g.38414801T>C c.1955A>G p.D652G RefSeq GRCh38/hg38
XM_006716304.2 chr8:g.38414801T>C c.1955A>G p.D652G RefSeq GRCh38/hg38
XM_017013221 chr8:g.38414801T>C c.1955A>G p.D652G RefSeq GRCh38/hg38
XM_017013220.1 chr8:g.38414888T>C c.1955A>G p.D652G RefSeq GRCh38/hg38
NM_023110 chr8:g.38414801T>C c.1955A>G p.D652G RefSeq GRCh38/hg38
XM_017013220 chr8:g.38414888T>C c.1955A>G p.D652G RefSeq GRCh38/hg38
XM_006716304 chr8:g.38414801T>C c.1955A>G p.D652G RefSeq GRCh38/hg38
XM_006716304.1 chr8:g.38414801T>C c.1955A>G p.D652G RefSeq GRCh38/hg38
XM_017013219.1 chr8:g.38414888T>C c.1955A>G p.D652G RefSeq GRCh38/hg38
XM_006716303.4 chr8:g.38414801T>C c.1955A>G p.D652G RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References