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Gene | FGFR1 |
Variant | D652G |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | FGFR1 D652G lies within the protein kinase domain of the Fgfr1 protein (UniProt.org). D652G has been identified in sequencing studies (PMID: 26920151, PMID: 32059187, PMID: 35836307), but has not been biochemically characterized and therefore, its effect on Fgfr1 protein function is unknown (PubMed, Mar 2024). |
Associated Drug Resistance | |
Category Variants Paths |
FGFR1 mutant FGFR1 D652G |
Transcript | NM_023110.3 |
gDNA | chr8:g.38414801T>C |
cDNA | c.1955A>G |
Protein | p.D652G |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
XM_017013219.2 | chr8:g.38414888T>C | c.1955A>G | p.D652G | RefSeq | GRCh38/hg38 |
XM_017013220.2 | chr8:g.38414888T>C | c.1955A>G | p.D652G | RefSeq | GRCh38/hg38 |
NM_023110 | chr8:g.38414801T>C | c.1955A>G | p.D652G | RefSeq | GRCh38/hg38 |
XM_017013219.1 | chr8:g.38414888T>C | c.1955A>G | p.D652G | RefSeq | GRCh38/hg38 |
XM_017013220.1 | chr8:g.38414888T>C | c.1955A>G | p.D652G | RefSeq | GRCh38/hg38 |
XM_006716303 | chr8:g.38414801T>C | c.1955A>G | p.D652G | RefSeq | GRCh38/hg38 |
XM_006716304 | chr8:g.38414801T>C | c.1955A>G | p.D652G | RefSeq | GRCh38/hg38 |
XM_006716304.2 | chr8:g.38414801T>C | c.1955A>G | p.D652G | RefSeq | GRCh38/hg38 |
XM_006716304.1 | chr8:g.38414801T>C | c.1955A>G | p.D652G | RefSeq | GRCh38/hg38 |
XM_017013219 | chr8:g.38414888T>C | c.1955A>G | p.D652G | RefSeq | GRCh38/hg38 |
XM_017013221.1 | chr8:g.38414801T>C | c.1955A>G | p.D652G | RefSeq | GRCh38/hg38 |
NM_023110.2 | chr8:g.38414801T>C | c.1955A>G | p.D652G | RefSeq | GRCh38/hg38 |
NM_023110.3 | chr8:g.38414801T>C | c.1955A>G | p.D652G | RefSeq | GRCh38/hg38 |
XM_017013220 | chr8:g.38414888T>C | c.1955A>G | p.D652G | RefSeq | GRCh38/hg38 |
XM_006716303.3 | chr8:g.38414801T>C | c.1955A>G | p.D652G | RefSeq | GRCh38/hg38 |
XM_017013221 | chr8:g.38414801T>C | c.1955A>G | p.D652G | RefSeq | GRCh38/hg38 |
XM_017013221.2 | chr8:g.38414801T>C | c.1955A>G | p.D652G | RefSeq | GRCh38/hg38 |
XM_006716303.4 | chr8:g.38414801T>C | c.1955A>G | p.D652G | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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