Gene Variant Detail

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Gene FGFR1
Variant D133E
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR1 D133E lies within the extracellular domain of the Fgfr1 protein (UniProt.org). D133E has been identified in sequencing studies (PMID: 25148578), but has not been biochemically characterized and therefore, its effect on Fgfr1 protein function is unknown (PubMed, Apr 2024).
Associated Drug Resistance
Category Variants Paths

FGFR1 mutant FGFR1 D133E

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Transcript NM_023110.3
gDNA chr8:g.38428395G>C
cDNA c.399C>G
Protein p.D133E
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_006716303 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_017013221.2 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_047421570.1 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_017013221.1 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_017013223 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_001354367.2 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_001354369.1 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_015850.3 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_017013228 chr8:g.38426195G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_017013225.3 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_006716304.2 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_001354367.1 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_047421574.1 chr8:g.38426195G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_001174063 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_047421569.1 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_023110 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_015850 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_017013221 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_006716307 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_006716306 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_001354368.1 chr8:g.38426195G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_006716303.3 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_001174065.2 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_017013225.2 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_006716304.1 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_006716304 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_001354369.2 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_017013222 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_017013222.2 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_023110.3 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_006716314.3 chr8:g.38426195G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_001354370.1 chr8:g.38426195G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_006716307.2 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_023106 chr8:g.38426195G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_001174065 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_017013224.2 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_001174065.1 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_006716314.2 chr8:g.38426195G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_001410922.1 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_001174063.2 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_006716314 chr8:g.38426195G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_001354370.2 chr8:g.38426195G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_023110.2 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_001354368.2 chr8:g.38426195G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_006716307.1 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_006716313 chr8:g.38426195G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_017013225 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_006716303.4 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_001174063.1 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
XM_017013224 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_023106.2 chr8:g.38426195G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_023106.3 chr8:g.38426195G>C c.399C>G p.D133E RefSeq GRCh38/hg38
NM_015850.4 chr8:g.38428395G>C c.399C>G p.D133E RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References