Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Gene Variant Descriptions||ABL1 F486S lies within the protein kinase domain of the Abl1 protein (UniProt.org). F486S has been demonstrated to occur as a secondary resistance mutation in the context of BCR-ABL1 (PMID: 23044928), but has not been biochemically characterized and therefore, its effect on Abl1 protein function is unknown (PubMed, Nov 2022).|
|Associated Drug Resistance|
|Category Variants Paths||
ABL1 mutant ABL1 F486S
|Transcript||gDNA||cDNA||Protein||Source Database||Genome Build|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status||Covered Countries||Other Countries|