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Gene | FANCL |
Variant | R10G |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | FANCL R10G does not lie within any known functional domains of the Fancl protein (UniProt.org). R10G has not been characterized in the scientific literature and therefore, its effect on Fancl protein function is unknown (PubMed, Mar 2024). |
Associated Drug Resistance | |
Category Variants Paths |
FANCL mutant FANCL R10G |
Transcript | NM_018062.4 |
gDNA | chr2:g.58241286G>C |
cDNA | c.28C>G |
Protein | p.R10G |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_001114636.1 | chr2:g.58241286G>C | c.28C>G | p.R10G | RefSeq | GRCh38/hg38 |
XM_011532939.3 | chr2:g.58241286G>C | c.28C>G | p.R10G | RefSeq | GRCh38/hg38 |
NM_001114636.1 | chr2:g.58241286G>C | c.28C>G | p.R10G | RefSeq | GRCh38/hg38 |
XM_047444852.1 | chr2:g.58241286G>C | c.28C>G | p.R10G | RefSeq | GRCh38/hg38 |
XM_011532940.4 | chr2:g.58241286G>C | c.28C>G | p.R10G | RefSeq | GRCh38/hg38 |
XM_011532940.3 | chr2:g.58241286G>C | c.28C>G | p.R10G | RefSeq | GRCh38/hg38 |
XM_005264395.5 | chr2:g.58241286G>C | c.28C>G | p.R10G | RefSeq | GRCh38/hg38 |
XM_011532939.4 | chr2:g.58241286G>C | c.28C>G | p.R10G | RefSeq | GRCh38/hg38 |
NM_018062.3 | chr2:g.58241286G>C | c.28C>G | p.R10G | RefSeq | GRCh38/hg38 |
XM_017004415.2 | chr2:g.58241286G>C | c.28C>G | p.R10G | RefSeq | GRCh38/hg38 |
XM_047444853.1 | chr2:g.58241286G>C | c.28C>G | p.R10G | RefSeq | GRCh38/hg38 |
NM_001410792.1 | chr2:g.58241286G>C | c.28C>G | p.R10G | RefSeq | GRCh38/hg38 |
XM_017004414.2 | chr2:g.58241286G>C | c.28C>G | p.R10G | RefSeq | GRCh38/hg38 |
XM_047444854.1 | chr2:g.58241286G>C | c.28C>G | p.R10G | RefSeq | GRCh38/hg38 |
XM_011532942.3 | chr2:g.58241286G>C | c.28C>G | p.R10G | RefSeq | GRCh38/hg38 |
NM_001374615.1 | chr2:g.58241286G>C | c.28C>G | p.R10G | RefSeq | GRCh38/hg38 |
NM_018062.4 | chr2:g.58241286G>C | c.28C>G | p.R10G | RefSeq | GRCh38/hg38 |
XM_011532942.4 | chr2:g.58241286G>C | c.28C>G | p.R10G | RefSeq | GRCh38/hg38 |
XM_011532941.2 | chr2:g.58241286G>C | c.28C>G | p.R10G | RefSeq | GRCh38/hg38 |
XM_005264395.4 | chr2:g.58241286G>C | c.28C>G | p.R10G | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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