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Gene | KDR |
Variant | M1016K |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | KDR (VEGFR2) M1016K lies within the protein kinase domain of the Kdr (Vegfr2) protein (UniProt.org). M1016K has not been characterized and therefore, its effect on Kdr (Vegfr2) protein function is unknown (PubMed, Jan 2021). |
Associated Drug Resistance |
Transcript | NM_002253.3 |
gDNA | chr4:g.55092639A>T |
cDNA | c.3047T>A |
Protein | p.M1016K |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_002253 | chr4:g.55092639A>T | c.3047T>A | p.M1016K | RefSeq | GRCh38/hg38 |
NM_002253.3 | chr4:g.55092639A>T | c.3047T>A | p.M1016K | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
KDR M1016K | unknown |