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Gene | FGFR1 |
Variant | T26I |
Impact List | missense |
Protein Effect | no effect - predicted |
Gene Variant Descriptions | FGFR1 T26I lies within Ig-like C2-type domain 1 of the Fgfr1 protein (UniProt.org). T26I results in transformation activity similar to wild-type Fgfr1 in cultured cells (PMID: 34272467), and therefore, is predicted to have no effect on Fgfr1 protein function. |
Associated Drug Resistance | |
Category Variants Paths |
FGFR1 mutant FGFR1 T26I |
Transcript | NM_023110.3 |
gDNA | chr8:g.38457370G>A |
cDNA | c.77C>T |
Protein | p.T26I |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_023110.2 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_006716311.1 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
NM_023105.3 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
NM_023106.2 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
NM_001354368.2 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_006716312.2 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_017013222.2 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_047421573.1 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
NM_001354370.1 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_006716311.1 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_006716307.2 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_006716310.4 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
NM_001174066.2 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
NM_001354368.1 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_006716304.1 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
NM_001410922.1 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
NM_015850.3 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
NM_001354369.2 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
NM_001354369.1 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_006716314.3 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
NM_001174065.2 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_006716312.2 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_006716314.2 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
NM_023110.3 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_047421569.1 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_017013221.2 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
NM_001174065.1 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
NM_001174063.2 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_006716310.3 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
NM_023105.2 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
NM_001354367.2 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_006716303.4 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_047421574.1 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_017013221.1 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_017013225.2 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_047421570.1 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
NM_001354370.2 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_017013224.2 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_006716307.1 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_006716303.3 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
NM_001174066.1 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_006716304.2 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
NM_001354367.1 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
NM_001174063.1 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
NM_015850.4 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
NM_023106.3 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
XM_017013225.3 | chr8:g.38457370G>A | c.77C>T | p.T26I | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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