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Gene ARID1A
Variant Q2188*
Impact List nonsense
Protein Effect unknown
Gene Variant Descriptions ARID1A Q2188* results in a premature truncation of the Arid1a protein at amino acid 2188 of 2285 (UniProt.org). Q2188* has been identified in sequencing studies (PMID: 22722193), but has not been biochemically characterized and therefore, its effect on Arid1a protein function is unknown (PubMed, Oct 2023).
Associated Drug Resistance
Category Variants Paths

ARID1A mutant ARID1A Q2188*

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Transcript NM_006015.6
gDNA chr1:g.26780460C>T
cDNA c.6562C>T
Protein p.Q2188*
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_006015.5 chr1:g.26780460C>T c.6562C>T p.Q2188* RefSeq GRCh38/hg38
NM_006015.6 chr1:g.26780460C>T c.6562C>T p.Q2188* RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References