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Gene | APC |
Variant | A1225G |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | APC A1225G does not lie within any known functional domains of the Apc protein (UniProt.org). A1225G has not been characterized in the scientific literature and therefore, its effect on Apc protein function is unknown (PubMed, Dec 2023). |
Associated Drug Resistance | |
Category Variants Paths |
APC mutant APC A1225G |
Transcript | NM_000038.6 |
gDNA | chr5:g.112839268C>G |
cDNA | c.3674C>G |
Protein | p.A1225G |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_001354895.1 | chr5:g.112839268C>G | c.3674C>G | p.A1225G | RefSeq | GRCh38/hg38 |
NM_001354904.2 | chr5:g.112839646C>G | c.3674C>G | p.A1225G | RefSeq | GRCh38/hg38 |
NM_001407450.1 | chr5:g.112839268C>G | c.3674C>G | p.A1225G | RefSeq | GRCh38/hg38 |
NM_001127510.3 | chr5:g.112839268C>G | c.3674C>G | p.A1225G | RefSeq | GRCh38/hg38 |
NM_000038.6 | chr5:g.112839268C>G | c.3674C>G | p.A1225G | RefSeq | GRCh38/hg38 |
NM_000038.5 | chr5:g.112839268C>G | c.3674C>G | p.A1225G | RefSeq | GRCh38/hg38 |
NM_001354895.2 | chr5:g.112839268C>G | c.3674C>G | p.A1225G | RefSeq | GRCh38/hg38 |
NM_001354902.2 | chr5:g.112839541C>G | c.3674C>G | p.A1225G | RefSeq | GRCh38/hg38 |
NM_001354906.2 | chr5:g.112840117C>G | c.3674C>G | p.A1225G | RefSeq | GRCh38/hg38 |
NM_001127510.2 | chr5:g.112839268C>G | c.3674C>G | p.A1225G | RefSeq | GRCh38/hg38 |
NM_001407470.1 | chr5:g.112840117C>G | c.3674C>G | p.A1225G | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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