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Gene | CTNNB1 |
Variant | G34L |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | CTNNB1 G34L lies within the ubiquitination recognition motif of the Ctnnb1 protein (PMID: 15064718). G34L has been identified in the scientific literature (PMID: 27334220), but has not been biochemically characterized and therefore, its effect on Ctnnb1 protein function is unknown (PubMed, Jul 2024). |
Associated Drug Resistance | |
Category Variants Paths |
CTNNB1 mutant CTNNB1 G34L |
Transcript | NM_001098210.2 |
gDNA | chr3:g.41224612_41224613delGGinsCT |
cDNA | c.100_101delGGinsCT |
Protein | p.G34L |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
XM_047447483.1 | chr3:g.41224612_41224613delGGinsCT | c.100_101delGGinsCT | p.G34L | RefSeq | GRCh38/hg38 |
XM_047447478.1 | chr3:g.41224612_41224613delGGinsCT | c.100_101delGGinsCT | p.G34L | RefSeq | GRCh38/hg38 |
XM_017005738.2 | chr3:g.41224612_41224613delGGinsCT | c.100_101delGGinsCT | p.G34L | RefSeq | GRCh38/hg38 |
XM_006712985.1 | chr3:g.41224612_41224613delGGinsCT | c.100_101delGGinsCT | p.G34L | RefSeq | GRCh38/hg38 |
XM_024453356.2 | chr3:g.41224612_41224613delGGinsCT | c.100_101delGGinsCT | p.G34L | RefSeq | GRCh38/hg38 |
XM_047447479.1 | chr3:g.41224612_41224613delGGinsCT | c.100_101delGGinsCT | p.G34L | RefSeq | GRCh38/hg38 |
XM_006712985.2 | chr3:g.41224612_41224613delGGinsCT | c.100_101delGGinsCT | p.G34L | RefSeq | GRCh38/hg38 |
XM_024453356.1 | chr3:g.41224612_41224613delGGinsCT | c.100_101delGGinsCT | p.G34L | RefSeq | GRCh38/hg38 |
XM_024453358.1 | chr3:g.41224612_41224613delGGinsCT | c.100_101delGGinsCT | p.G34L | RefSeq | GRCh38/hg38 |
XM_017005738.1 | chr3:g.41224612_41224613delGGinsCT | c.100_101delGGinsCT | p.G34L | RefSeq | GRCh38/hg38 |
XM_047447481.1 | chr3:g.41224612_41224613delGGinsCT | c.100_101delGGinsCT | p.G34L | RefSeq | GRCh38/hg38 |
XM_024453357.1 | chr3:g.41224612_41224613delGGinsCT | c.100_101delGGinsCT | p.G34L | RefSeq | GRCh38/hg38 |
NM_001098210.1 | chr3:g.41224612_41224613delGGinsCT | c.100_101delGGinsCT | p.G34L | RefSeq | GRCh38/hg38 |
NM_001098209.2 | chr3:g.41224612_41224613delGGinsCT | c.100_101delGGinsCT | p.G34L | RefSeq | GRCh38/hg38 |
NM_001098210.2 | chr3:g.41224612_41224613delGGinsCT | c.100_101delGGinsCT | p.G34L | RefSeq | GRCh38/hg38 |
XM_047447477.1 | chr3:g.41224612_41224613delGGinsCT | c.100_101delGGinsCT | p.G34L | RefSeq | GRCh38/hg38 |
NM_001098209.1 | chr3:g.41224612_41224613delGGinsCT | c.100_101delGGinsCT | p.G34L | RefSeq | GRCh38/hg38 |
NM_001904.3 | chr3:g.41224612_41224613delGGinsCT | c.100_101delGGinsCT | p.G34L | RefSeq | GRCh38/hg38 |
NM_001904.4 | chr3:g.41224612_41224613delGGinsCT | c.100_101delGGinsCT | p.G34L | RefSeq | GRCh38/hg38 |
XM_047447480.1 | chr3:g.41224612_41224613delGGinsCT | c.100_101delGGinsCT | p.G34L | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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