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Gene ERBB4
Variant K1223M
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ERBB4 K1223M lies within the cytoplasmic domain of the Erbb4 protein (UniProt.org). K1223M has not been characterized in the scientific literature and therefore, its effect on Erbb4 protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

ERBB4 mutant ERBB4 K1223M

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Transcript NM_005235.3
gDNA chr2:g.211383874T>A
cDNA c.3668A>T
Protein p.K1223M
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_017003578.2 chr2:g.211383952T>A c.3668A>T p.K1223M RefSeq GRCh38/hg38
NM_005235.3 chr2:g.211383874T>A c.3668A>T p.K1223M RefSeq GRCh38/hg38
XM_017003578.3 chr2:g.211383952T>A c.3668A>T p.K1223M RefSeq GRCh38/hg38
NM_005235.2 chr2:g.211383874T>A c.3668A>T p.K1223M RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References