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Gene FBXW7
Variant E287K
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FBXW7 E287K lies within the F-box domain of the Fbxw7 protein (UniProt.org). E287K has not been characterized in the scientific literature and therefore, its effect on Fbxw7 protein function is unknown (PubMed, Feb 2024).
Associated Drug Resistance
Category Variants Paths

FBXW7 mutant FBXW7 E287K

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Transcript NM_033632.3
gDNA chr4:g.152337804C>T
cDNA c.859G>A
Protein p.E287K
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_011532084.3 chr4:g.152337804C>T c.859G>A p.E287K RefSeq GRCh38/hg38
NM_033632.3 chr4:g.152337804C>T c.859G>A p.E287K RefSeq GRCh38/hg38
NM_033632.3 chr4:g.152337804C>T c.859G>A p.E287K RefSeq GRCh38/hg38
NM_001349798.2 chr4:g.152337804C>T c.859G>A p.E287K RefSeq GRCh38/hg38
XM_047415898.1 chr4:g.152337804C>T c.859G>A p.E287K RefSeq GRCh38/hg38
XM_024454124.1 chr4:g.152337804C>T c.859G>A p.E287K RefSeq GRCh38/hg38
XM_047415901.1 chr4:g.152337804C>T c.859G>A p.E287K RefSeq GRCh38/hg38
XM_024454121.1 chr4:g.152337804C>T c.859G>A p.E287K RefSeq GRCh38/hg38
XM_011532085.2 chr4:g.152337804C>T c.859G>A p.E287K RefSeq GRCh38/hg38
XM_024454123.1 chr4:g.152337804C>T c.859G>A p.E287K RefSeq GRCh38/hg38
NM_001349798.1 chr4:g.152337804C>T c.859G>A p.E287K RefSeq GRCh38/hg38
XM_024454123.2 chr4:g.152337804C>T c.859G>A p.E287K RefSeq GRCh38/hg38
XM_047415897.1 chr4:g.152337804C>T c.859G>A p.E287K RefSeq GRCh38/hg38
XM_047415899.1 chr4:g.152337804C>T c.859G>A p.E287K RefSeq GRCh38/hg38
XM_011532085.3 chr4:g.152337804C>T c.859G>A p.E287K RefSeq GRCh38/hg38
XM_047415900.1 chr4:g.152337804C>T c.859G>A p.E287K RefSeq GRCh38/hg38
XM_024454122.1 chr4:g.152337804C>T c.859G>A p.E287K RefSeq GRCh38/hg38
XM_011532084.2 chr4:g.152337804C>T c.859G>A p.E287K RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References