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Gene FBXW7
Variant R393Q
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FBXW7 R393Q lies within WD repeat 1 of the Fbxw7 protein (UniProt.org). R393Q has been identified in the scientific literature (PMID: 31195063), but has not been biochemically characterized and therefore, its effect on Fbxw7 protein function is unknown (PubMed, Mar 2024).
Associated Drug Resistance
Category Variants Paths

FBXW7 mutant FBXW7 R393Q

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Transcript NM_033632.3
gDNA chr4:g.152329730C>T
cDNA c.1178G>A
Protein p.R393Q
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_047415897.1 chr4:g.152329730C>T c.1178G>A p.R393Q RefSeq GRCh38/hg38
XM_047415899.1 chr4:g.152329730C>T c.1178G>A p.R393Q RefSeq GRCh38/hg38
XM_047415900.1 chr4:g.152329730C>T c.1178G>A p.R393Q RefSeq GRCh38/hg38
XM_047415898.1 chr4:g.152329730C>T c.1178G>A p.R393Q RefSeq GRCh38/hg38
NM_001349798.1 chr4:g.152329730C>T c.1178G>A p.R393Q RefSeq GRCh38/hg38
NM_001349798.2 chr4:g.152329730C>T c.1178G>A p.R393Q RefSeq GRCh38/hg38
NM_033632.3 chr4:g.152329730C>T c.1178G>A p.R393Q RefSeq GRCh38/hg38
XM_047415901.1 chr4:g.152329730C>T c.1178G>A p.R393Q RefSeq GRCh38/hg38
XM_024454124.1 chr4:g.152329730C>T c.1178G>A p.R393Q RefSeq GRCh38/hg38
XM_024454121.1 chr4:g.152329730C>T c.1178G>A p.R393Q RefSeq GRCh38/hg38
NM_033632.3 chr4:g.152329730C>T c.1178G>A p.R393Q RefSeq GRCh38/hg38
XM_011532085.3 chr4:g.152329730C>T c.1178G>A p.R393Q RefSeq GRCh38/hg38
XM_024454123.1 chr4:g.152329730C>T c.1178G>A p.R393Q RefSeq GRCh38/hg38
XM_011532084.3 chr4:g.152329730C>T c.1178G>A p.R393Q RefSeq GRCh38/hg38
XM_011532084.2 chr4:g.152329730C>T c.1178G>A p.R393Q RefSeq GRCh38/hg38
XM_011532085.2 chr4:g.152329730C>T c.1178G>A p.R393Q RefSeq GRCh38/hg38
XM_024454123.2 chr4:g.152329730C>T c.1178G>A p.R393Q RefSeq GRCh38/hg38
XM_024454122.1 chr4:g.152329730C>T c.1178G>A p.R393Q RefSeq GRCh38/hg38

Filtering

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References